Manipulating mitochondrial networks could promote healthy aging

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According to Medical Xpress



Manipulating mitochondrial networks inside cells—either by dietary restriction or by genetic manipulation that mimics it—may increase lifespan and promote health, according to new research from Harvard T.H. Chan School of Public Health.

The study, published online October 26, 2017 in Cell Metabolism, sheds light on the basic biology involved in cells’ declining ability to process energy over time, which leads to aging and age-related disease, and how interventions such as periods of  might promote healthy aging.

Mitochondria—the energy-producing structures in cells—exist in networks that dynamically change shape according to energy demand. Their capacity to do so declines with age, but the impact this has on metabolism and cellular function was previously unclear. In this study, the researchers showed a causal link between dynamic changes in the shapes of mitochondrial networks and longevity.



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This article and images were originally posted on [Medical Xpress] October 26, 2017 at 12:07PM

Credit to Author and Medical Xpress






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