Somatic APP gene recombination in Alzheimer’s disease and normal neurons

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According to (This article and its images were originally posted on Nature November 21, 2018 at 01:11PM.)

The diversity and complexity of the human brain are widely assumed to be encoded within a constant genome. Somatic gene recombination, which changes germline DNA sequences to increase molecular diversity, could theoretically alter this code but has not been documented in the brain, to our knowledge.
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This article and images were originally posted on [Nature] November 21, 2018 at 01:11PM. Credit to the original author and Nature | ESIST.T>G>S Recommended Articles Of The Day.




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