Brain plasticity restored in adult mice through targeting specific nerve cell connections

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According to (This article and its images were originally posted on Latest Science News — ScienceDaily January 8, 2019 at 06:56PM.)

Neuroscientists at Tufts University School of Medicine, in collaboration with colleagues at Yale University School of Medicine, have discovered a new molecular mechanism that is essential for maturation of brain function and may be used to restore plasticity in aged brains. Unlike previous research that broadly manipulated brain plasticity using approaches that affected the entire brain, this study targets for the first time a specific molecule acting on a single type of neuronal connection to modulate brain function. This restores the brain’s ability to rewire itself.
The research in mice could advance understanding and treatment of human diseases such as autism spectrum disorders and stroke. It is published in Cell Reports on January 8, 2019.The human brain is very plastic during childhood, and all young mammals have a “critical period” when different areas of their brains can remodel neural connections in response to external stimuli. Disruption of this precise developmental sequence results in serious damage; conditions such as autism potentially involve disrupted critical periods.

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This article and images were originally posted on [Latest Science News — ScienceDaily] January 8, 2019 at 06:56PM. Credit to the original author and Latest Science News — ScienceDaily | ESIST.T>G>S Recommended Articles Of The Day.

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