The Case for Transmissible Alzheimer’s Grows

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According to (This article and its images were originally posted on Scientific American Content February 9, 2019 at 03:04PM.)

The unsettling evidence that Alzheimer’s Disease may be transmissible under limited — but definitely nonzero — circumstances keeps growing.

Last December I wrote about research that revealed that infectious, lethal proteins called prions have the potential to be transmitted on optical medical equipment because they are present throughout the eyes of victims.

This was all the more disturbing in light of a study I had also recently written about that suggested that peptide aggregates – essentially sticky, self-propagating clumps of misfolded protein bits collectively referred to as amyloid — found in the brains of Alzheimer’s patients may be transmissible in the same ways that prions are.

Then, just a few days after I wrote about the prion eye hazard, a new paper appeared in Nature that seemed to take the evidence for the transmissibility of Alzheimer’s peptides from “circumstantial” to “experimentally produced”. It is fascinating, if unsettling, news, that further blurs the line between amyloid and prions.


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This article and images were originally posted on [Scientific American Content] February 9, 2019 at 03:04PM. Credit to the original author and Scientific American Content | ESIST.T>G>S Recommended Articles Of The Day.


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